‘Kambo’ or ‘Sapo’ is the frog medicine of the Phyllomedusa bicolour, or Amazonian tree frog, ustilised by the indigenous people of the Amazon going back to prerecorded history. It is an anti-parasite, anti-viral, anti-fungal, anti-bacterial, anti-inflammatory, anti-fatigue, anti-depressant, anti-addiction compound that is very effective at eliminating toxins from the body while delivering peptides that cross the blood-brain barrier and help the brain send messages to the rest of the body, resulting in an all round immune system boost and sense of well-being. The frog is highly respected and not harmed during the collection of the medicine. The administration of the medicine consists of making one or more small burns to remove the top layer of skin, to allow the medicine to be applied and enter the bloodstream. A brief period of unpleasantness and nausea can ensue resulting in the purging of toxins from the body. Generally. the recipient is back to feeling normal within 20 minutes.